fitmylensthe lens-by-mount reference
Choose camera

Canon RF 75-300mm f/4-5.6 DC vs Canon RF 100-300mm f/2.8 L IS USM

Both are Canon RF mount zooms for telephoto and sports & action — here's how the specs differ and which to pick. Every spec is from the manufacturer's own catalog.

Last verified 2026-09-01 · Canon RF mount · prices change — check the retailer

SpecCanon RF 75-300mm f/4-5.6 DCCanon RF 100-300mm f/2.8 L IS USM
Focal length75-300mm100-300mm
Max aperturef/4-5.6f/2.8
Typezoomzoom
Coveragefull-framefull-frame
MountCanon RFCanon RF

Which should you buy?

Where to buy

Canon RF75-300mm F4-5.6, Telephoto Zoom Lens, Compatible with EOS R Series Mirrorless Cameras, Black

Canon RF 75-300mm f/4-5.6 DCSee price on Amazon

Amazon links are affiliate links — we may earn a commission at no extra cost to you.

Canon RF100-300mm F2.8 L is USM, RF Lens, Mirrorless, Telephoto Zoom, Optical Image Stabilization, Professional, High-en

Canon RF 100-300mm f/2.8 L IS USMSee price on Amazon

As an Amazon Associate we earn from qualifying purchases, at no extra cost to you. Affiliate links never affect our specs or which lenses we compare.

FAQ

What's the difference between the Canon RF 75-300mm f/4-5.6 DC and the Canon RF 100-300mm f/2.8 L IS USM?
The Canon RF 75-300mm f/4-5.6 DC is 75-300mm f/4-5.6 zoom, full-frame; the Canon RF 100-300mm f/2.8 L IS USM is 100-300mm f/2.8 zoom, full-frame. Both fit the Canon RF mount.

Which is better in low light, the Canon RF 75-300mm f/4-5.6 DC or the Canon RF 100-300mm f/2.8 L IS USM?
The Canon RF 100-300mm f/2.8 L IS USM — its f/2.8 maximum aperture lets in more light and gives more background blur than the f/4-5.6 of the other.

Do the Canon RF 75-300mm f/4-5.6 DC and Canon RF 100-300mm f/2.8 L IS USM fit the same camera?
Yes — both are Canon RF mount lenses, so they fit Canon EOS R series (full-frame R5/R6/R8) and APS-C (R7/R10/R50).

Citing these specs? Go ahead — manufacturer data, last verified 2026-09-01. Copy a ready-made reference:

More Canon RF comparisons: Canon RF 24-70mm f/2.8 L IS USM vs Canon RF-S 18-150mm f/3.5-6.3 IS STM · Canon RF 24mm f/1.4 L VCM vs Canon RF 28mm f/2.8 STM · Canon RF 800mm f/5.6 L IS USM vs Canon RF 1200mm f/8 L IS USM · Canon RF 100mm f/2.8 L Macro IS USM vs Laowa 100mm f/2.8 2x Ultra Macro APO · all Canon RF lenses · all comparisons

Canon RF 75-300mm f/4-5.6 DCAffiliate linkSee price on Amazon

Find FitMyLens in your Google results more often: